the pallidotomy marginally helped a lot of things. It
not only got rid of the hellish dyskinesia.  Since my
                     PVP I dfont have Migrains any
more I bagan sleeping all night,  I was able to drive
again,my PD medications started to work again they
hadn't been working

David Moreland



--- "Nancy S. deGrazia" <[log in to unmask]>
wrote:
> David - that's good to hear.  Were your PD symptoms
> across the board
> (tremor, gait problems,  freezing, etc)? And which
> ones did the
> pallidotomy help?
>
> Nancy deG
>
> David Moreland wrote:
>
> >--- "Nancy S. deGrazia" <[log in to unmask]>
> >wrote:
> >
> >
> >>Thank you, Chris :
> >>No. my "end of dose " phenomenom is the onset of
> >>dyskinesia. I seem to
> >>have both "peak dose" and "end of dose"
> dyskinesia.
> >>I have been taking
> >>sinemet for almost 10 years and over that period
> >>have added eldepryl,
> >>permax, mirapex and amantadine. I guess the reason
> I
> >>am taking so many
> >>different things is that I am hypersensitive to
> >>levadopa. I take 1/4 of
> >>a 25/100 every 90 minutes and if I take more the
> >>dyskinesia is just awful..
> >>
> >>Anyone else with this kind of problem?
> >>I used to have diskinesias  that on a 1  to  10
> >>
> >>
> >scale mine were up to 13 or 14 . Then i had a
> >pallidototomy.   For the most part I have been free
> of
> >dyskinesia  since then (1995}
> >David Moreland
> >
> >
> >>Nancy deG
> >>
> >>Chris Lui wrote:
> >>
> >>
> >>
> >>>Hi Nancy:
> >>>
> >>>My end of dose phenomenon refers to premature
> >>>
> >>>
> >>ending of the effectiveness of
> >>
> >>
> >>>the medicine, a shortened drug effect experienced
> >>>
> >>>
> >>after 3 years of
> >>
> >>
> >>>medication.  Have you got the similar problem?
> >>>
> >>>Chris Lui
> >>>
> >>>----- Original Message -----
> >>>From: "Nancy S. deGrazia"
> <[log in to unmask]>
> >>>To: <[log in to unmask]>
> >>>Sent: Tuesday, September 16, 2003 6:57 PM
> >>>Subject: Re: COMTAN
> >>>
> >>>
> >>>
> >>>
> >>>
> >>>
> >>>>Chris Lui:- iis the "end of dose" phenomenon you
> >>>>
> >>>>
> >>referred to (A) a
> >>
> >>
> >>>>premature ending of the effectiveness of the
> >>>>
> >>>>
> >>medecine or (b) dyskinesia
> >>
> >>
> >>>>which manifests itself at the end of a dose?
> >>>>
> >>>>Your response will clarify my situation for
> which
> >>>>
> >>>>
> >>I would be very
> >>
> >>
> >>>>
> >>>>
> >>>grateful.
> >>>
> >>>
> >>>
> >>>
> >>>>Nancy S deGrazia
> >>>>
> >>>>
> >>>>
> >>>>Chris Lui wrote:
> >>>>
> >>>>
> >>>>
> >>>>
> >>>>
> >>>>>Hi ALL,
> >>>>>
> >>>>>Today my neuro starts putting me on COMTAN to
> >>>>>
> >>>>>
> >>addrerss the end of dose
> >>
> >>
> >>>>>
> >>>>>
> >>>phenomenon.  Any one has got any advice or
> comment
> >>>
> >>>
> >>about the use of this
> >>
> >>
> >>>drug?  Be it favourable or adverse,  your
> >>>
> >>>
> >>experience would certainly help!
> >>
> >>
> >>>Thanks!
> >>>
> >>>
> >>>
> >>>
> >>>>>Chris Lui
> >>>>>
> >>>>>
> >>>>>
>
>>>>----------------------------------------------------------------------
> >>>>
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> >>>
> >>>
> >>>>>In the body of the message put: signoff
> parkinsn
> >>>>>
> >>>>>
> >>>>>
> >>>>>
> >>>>>
> >>>>>
> >>>>>
>
>>>----------------------------------------------------------------------
> >>>
> >>>
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