Raj,

Thanks for the very detailed reply.
Curious - why do you take Tumeric in stead of  Curcumin?

Nick

R.Rajaraman wrote:

>WARNING:
>        I AM TAKING A CALCULATED RISK IN PRESCIBING MY OWN MEDICATION. I DO
>THIS AFTER A THOROUGH LITERATURE SURVEY.
>        I AM SHARING MY EXPERIENCE. I AM NOT QUALIFIED TO GIVE ANY ADVICE TO
>ANYBODY. WHAT WORKS FOR ME MAY NOT WORK FOR EVERYBODY. DO CONSULT A
>QUALIFIED INDIVIDUL BEFORE YOU CHANGE ANYTHING THAT YOU ARE DOING CURRENTLY.
>
>Hi Nick & Oanh:
>    Anybody who knows about the action of sinamet, will opt to stay out of
>it as long as possible. That was and is my whole aim even today. It is
>unfortunate that no new and useful medication has been invented for the past
>several decades. I visited my neuro last week. The intern that saw me for
>almost 40 minutes was trying to push sinemet on me very hard. He sounded
>worse than the medical sales rep. He insisted that sinemet does not cause
>dyskenesia!
>    When I told him  that Cox-2 inhibitor is important for slowing the
>progression of PD, he didn't even know about it. That is the kind of
>younger generation of doctors we are training!  After the chief had a talk
>with me, he said more or less the same thing. However, at the end of my
>visit, another intern came with a questionnaire that she was studying. This
>was about the bad side effects caused by sinamet and the patients aptitude
>with regard to taking sinemet. Both the interns were contradicting each
>other.
>    To cut the long story short, I still was not convinced enough to take
>sinemet. I have determined to sty out of it as long as I can manage.
>Therefore, I am still pursuing my multiprong attack and hope I can solve my
>problems. However, I must say that I have been so far lucky to drastically
>slow down the progression of PD. I cannot still say I have stopped the
>progression completely.
>    Here are the things that I take everyday:
>
>    Morning:
>    20 Min yoga and exercise*
>        Dr. Paneri's medication*
>        Synthroid (for hypothyroidism)
>        Acetyl-l-carnitine**
>        Folic acid for BP & nerves
>        B12
>        Celebrex 100 mg*
>        Brain essentials from Swanson's nutritionals*
>        Co E Q 10 for PD and heart *
>        Green tea capsule
>        MIX of blue berry and pomogranate juice (for Pd and heart)
>        bran cereal + almonds and walnuts
>
>Lunch time:
>        Dr. Paneri's medication
>        Acetyl-l-carnitine
>        Atacand (for Blood Pressure)
>        L-Carnosine**
>        Co E Q10
>        Chondroitin/glucoasmine caps.
>        Multivitamin
>    Omega 3 oil or salmon oil on alternate days or when I don't consume
>salmon for a few days..
>        Brain essentials*
>        Light lunch with fruits and juices
>
>Supper  time:
>        Dr. Paneri's medication
>        Aceyl-l-carnitine
>        Resveratrol**
>        Brain essentials
>        Turmeric caps  400 mg   (for PD and general health of nerves)
>        Supper with salads, fish or chicken no rice (low carb diet)
>
>before bed time:
>        Atacand for BP.
>    Listen to the Mind Aerobics tape**
>
>*THese items I find very useful.
>** These items have anti-aging, anti-inflammatory, anti-oxidnt,
>neuroprotective and neuro regenerative properties. These should be consumed
>by everybody for general health.
>
>    In general, I avoid beef, rice, and white bread, when ever possible.
>    I consume plenty of stuff like spinach and stawberries (both great for
>PD). I make it a point to take a variety of fruits, not necessarily all at
>the same time. The idea is to consume anti-inflammatory, neuroprotective,
>neuro-regenerative, and antioxidants as much as possible.
>WARNING:
>        I AM TAKING A CALCULATED RISK IN PRESCIBING MY OWN MEDICATION. I DO
>THIS AFTER A THOROUGH LITERATURE SURVEY.
>        I AM SHARING MY EXPERIENCE. I AM NOT QUALIFIED TO GIVE ANY ADVICE TO
>ANYBODY. WHAT WORKS FOR ME MAY NOT WORK FOR EVERYBODY. DO CONSULT A
>QUALIFIED INDIVIDUL BEFORE YOU CHANGE ANYTHING THAT YOU ARE DOING CURRENTLY.
> I was diagnosed in 1999. It too me two yearss bfore I understood the
>seriousness of PD and he  woes of allopathic PD medications. I wish I
>started on my protocol much earlier.
>    However, I must say that my friends, including doctors, and my  two
>sons, who are doctors themselves, tell me that I look a lot better than I
>use to a couple of years ago.  In fact, a medical doctor friend of mine was
>so impressed with my health improvement, he is prescribing the same things
>to his patient, who did not respond well of the conventional medicines.
>    I must add that I am painfully aware that I am not out of the woods yet.
>If everything else fails, I can always starting on sinemet, which would be
>my last option. I am still on constant look out for alternative medications
>for my PD.
>
>    I hope I have answered your questions.
>    Wishing you all the best.
>    Raj
>********************
>----- Original Message -----
>From: "Nick & Oanh" <[log in to unmask]>
>To: <[log in to unmask]>
>Sent: Saturday, April 02, 2005 6:19 AM
>Subject: Curcumin inhibits neuronal cell death
>
>
>
>
>>Hi Raj,
>>Been following your posts, and the novel way you are combating PD.
>>
>>Would you be so kind and let us know what you are taking now, and how
>>well it's working for you?
>>
>>Thanks in advance,
>>Nick
>>
>>Brightline wrote:
>>
>>
>>
>>>Hi Everybody:
>>>   I was aware that curcumin, an active component of the Indian spice &
>>>
>>>
>condiment, turmeric, has some protective action against PD and also has
>certain cancer-killing effect.  The consumption of turmeric is thought to be
>one of the reasons why PD is rare in Indian population. However, I did not
>know the mechanism of its action. Recently, I ran into some interesting
>references that claim curcumin inhibits the death of dopaminergic neurons in
>the MPP+ Parkinson's disease model (Neuropharmacology 2002, 42, 1056-64) by
>inhibiting an enzyme that triggers cell death or apoptosis.  I also found
>some references to the effect that Omega 3 Fatty Acid (good for the heart
>too)  also acts in a similar fashion
>
>
>>>   Therefore, I have added these two in my arsenal against the
>>>
>>>
>advacement of PD.  This is for your info only.
>
>
>>>   Please talk to your physician before you change anything.
>>>   Wish you all the best.
>>>   Raj
>>>*********
>>>
>>>----------------------------------------------------------------------
>>>To sign-off Parkinsn send a message to:
>>>
>>>
>mailto:[log in to unmask]
>
>
>>>In the body of the message put: signoff parkinsn
>>>
>>>
>>>
>>>
>>>
>>----------------------------------------------------------------------
>>To sign-off Parkinsn send a message to:
>>
>>
>mailto:[log in to unmask]
>
>
>>In the body of the message put: signoff parkinsn
>>
>>
>
>----------------------------------------------------------------------
>To sign-off Parkinsn send a message to: mailto:[log in to unmask]
>In the body of the message put: signoff parkinsn
>
>
>

----------------------------------------------------------------------
To sign-off Parkinsn send a message to: mailto:[log in to unmask]
In the body of the message put: signoff parkinsn