Tumeric considered an antiseptic, is used in very small quantities in
cooking curry primarly for colour/tradition wonder what quantities are being
talked about would be interested in details.
Haroon Basheer
Chairman
Pakistan Parkinson's Society
www.parkinsons.org.pk
karachi

2008/6/15 rockiepark <[log in to unmask]>:

> On May 28, 2008, at 8:24:42 AM, "Moneesha Sharma" <
> [log in to unmask]> wrote:
> From:   "Moneesha Sharma"
> Subject:    Re: Turmeric for Parkinson's
> Date:   May 28, 2008 8:24:42 AM EDT
> To: [log in to unmask]
> Amazing! We use turmeric almost every day in our cooking but probably not
> in the kinds of quantities that would make a difference.
>
> NIMHANS in Bangalore is a very reputed institution.
>
> Moneesha
> Wife of Prem 62/56/54? Calcutta, India
>
>
>
> On Wed, May 28, 2008 at 2:51 PM, M.Schild <[log in to unmask]> wrote:
>
> > Turmeric for Parkinson's
> >
> > Subhra Priyadarshini
> > The researchers: Mythri, Bharath, JagathaThe researchers: Mythri,
> Bharath,
> > Jagatha
> >
> > Curcumin, the wonder compound in turmeric, has found another possible
> > therapeutic use — this time for treatment of Parkinson's Disease1.
> >
> > Researchers conducting experiments on mice have shown that curcumin
> > increased
> > the content of glutathione (GSH), an anti-oxidant in certain nerve cells
> of
> > the brain that control body movement. The increased GSH protects the
> brain
> > against abnormal accumulation of toxic free radicals that damage the
> > mitochondria of these nerve cells triggering off Parkinson's Disease
> (PD).
> >
> > "During Parkinson's, there is a gradual death of specific nerve cells
> > called
> > dopaminergic neurons in the mid-brain. If we understand why these cells
> > die,
> > we can slow the process down or reverse it by developing better
> therapies,"
> > says M. M. Srinivas Bharath, the lead researcher.
> >
> > During early PD, there is a significant depletion of GSH leading to
> > abnormal
> > accumulation of toxic free radicals. These free radicals damage
> > mitochondria,
> > the powerhouse of the cell, ultimately killing the nerve cells. "So, if
> we
> > could prevent depletion of GSH in mid-brain nerve cells, we could protect
> > nerve cells against degeneration," Bharath says.
> >
> > The team found that selective GSH depletion in mid-brain nerve cells
> > damaged
> > mitochondria mimicking an early PD condition. To protect against this
> > insult,
> > they administered curcumin. The compound protected mouse brain and nerve
> > cells in culture by increasing the GSH content and protecting against
> toxic
> > free radicals thus exhibiting therapeutic potential in early PD.
> >
> > To support this conclusion, the team used computer simulations and
> > biochemical
> > experiments. They simulated disease pathways of PD using mathematics and
> > computer modeling to generate a virtual experimental system that gives a
> > complete picture of disease cascades and potential therapeutic targets.
> > Using
> > this 'in silico' model, they corroborated that curcumin could be a
> > potential
> > therapeutic compound in PD.
> >
> > The authors of this work are from: Department of Neurochemistry, National
> > Institute of Mental Health and Neurosciences, Hosur Road, Bangalore,
> > Karnataka, India; Cell works group Inc., Marathahalli, Bangalore & Pierce
> > Road, Saratoga, CA, USA.
> >
> > *
> >
> > ----------------------------------------------------------------------
> > To sign-off Parkinsn send a message to: mailto:
> > [log in to unmask]
> > In the body of the message put: signoff parkinsn
> >
>
> ----------------------------------------------------------------------
> To sign-off Parkinsn send a message to: mailto:
> [log in to unmask]
> In the body of the message put: signoff parkinsn
>
>
>
> ----------------------------------------------------------------------
> To sign-off Parkinsn send a message to: mailto:
> [log in to unmask]
> In the body of the message put: signoff parkinsn
>