To the best of my knowledge tyrosine has no impact on blood pressure. It is
a precursor necessary for the production of dopamine by the liver. It is
quite beneficial. Salt and sugar as well as poor diets have more impact on
BP .
Hope this helps.
If it werent for tyrosine in my program I couldnt do the 5 to 6 hours of
walking I've been doing the last few days fixing storm damage on the ranch
fences. Needless to say by sundown I'm really wornout for the day.
Have a good Sunday Ray.

----- Original Message -----
From: "rayilynlee" <[log in to unmask]>
To: <[log in to unmask]>
Sent: Friday, May 08, 2009 10:48 AM
Subject: Re: Question re milk thistle


> thanks Roberta  - I take bp medication
> Ray
>
> Rayilyn Brown
> Director AZNPF
> Arizona Chapter National Parkinson Foundation
> [log in to unmask]
>
> --------------------------------------------------
> From: <[log in to unmask]>
> Sent: Thursday, May 07, 2009 4:03 AM
> To: <[log in to unmask]>
> Subject: Re: Question re milk thistle
>
> >
> >
> > Doesn't Tyrosine increase blood pressure?
> >
> > Roberta Innarella
> >
> >
> > In a message dated 5/7/2009 2:01:57 A.M. Eastern Daylight Time,
> > [log in to unmask] writes:
> >
> > Yep!
> >
> > ----- Original Message -----
> > From:  "rayilynlee" <[log in to unmask]>
> > To:  <[log in to unmask]>
> > Sent: Tuesday, May 05, 2009  9:45 AM
> > Subject: Re: Question re milk thistle
> >
> >
> >> gee, I  didn't know milk thistle would help my liver produce dopamine.
> >> I
> >> started taking it for constipation.  Do I need to take  tyrosine with
it?
> >>
> >> Ray
> >>
> >> Rayilyn  Brown
> >> Director AZNPF
> >> Arizona Chapter National Parkinson  Foundation
> >> [log in to unmask]
> >>
> >>  --------------------------------------------------
> >> From: "Schaaf  Angus / Meadow Creek Ranch" <[log in to unmask]>
> >> Sent:  Tuesday, May 05, 2009 8:40 AM
> >> To:  <[log in to unmask]>
> >> Subject: Question re  Amantadine/  GSH importance
> >>
> >> > Couple of  thoughts.
> >> > Have you tried to let your liver produce your  dopamine needs by
taking
> >> > tyrosine and milk thistle?
> >>  > The natural production of GSH  by the body is a little more
> > complicated
> >> > but
> >> > following is article from my  archives that helps explain.
> >> >      WHY  GSH
> >> > Oxidative stress appears to play an important role in  degeneration
of
> >> > dopaminergic neurons of the substantia  nigra (SN) associated with
> >> > Parkinson's disease (PD). The SN  of early PD patients have
> >> > dramatically
> >> > decreased levels of  the thiol tripeptide glutathione (GSH). GSH
plays
> >> > multiple  roles in the nervous system both as an antioxidant and a
> >> > redox
> >>  > modulator. We have generated dopaminergic PC12 cell lines in  which
> > levels
> >> > of
> >> > GSH can be inducibly  down-regulated via doxycycline induction of
> > antisense
> >> >  messages against both the heavy and light subunits of
> >> >  gamma-glutamyl-cysteine synthetase, the rate-limiting enzyme in
> >>  > glutathione
> >> > synthesis. Down-regulation of  glutamyl-cysteine synthetase results
in
> >> > reduction in  mitochondrial GSH levels, increased oxidative stress,
and
> >> >  decreased mitochondrial function. Interestingly, decreases in
> >>  > mitochondrial
> >> > activities in GSH-depleted PC12 cells  appears to be because of a
> > selective
> >> > inhibition of  complex I activity as a result of thiol oxidation.
These
> >> >  results suggest that the early observed GSH losses in the SN may  be
> >> > directly
> >> > responsible for the noted  decreases in complex I activity and the
> >> > subsequent
> >>  > mitochondrial dysfunction, which ultimately leads to dopaminergic
> >> cell
> >> > death
> >> > associated with PD.
> >>  >
> >> >   WHY GLUTAMINE
> >> > Glutamine is an  important mitochondrial substrate implicated in the
> >> >  protection of cells from oxidant injury. Human pulmonary
> > epithelial-like
> >> > (A549) cells were exposed to 95% O(2) for 4  days in the absence and
> >> > presence
> >> > of glutamine.  Cell proliferation in normoxia was dependent on
> > glutamine,
> >> >  and
> >> > glutamine deprivation markedly accelerated cell death  in hyperoxia.
> >> > Glutamine significantly increased cellular  ATP levels in normoxia
and
> >> > prevented the loss of ATP in  hyperoxia seen in glutamine-deprived
> > cells.
> >> > Mitochondrial  membrane potential as assessed by flow cytometry with
> >> >  chloromethyltetramethylrosamine was increased by glutamine in
> >>  > hyperoxia-exposed A549 cells, and a glutamine dose-dependent
increase
> > in
> >> > mitochondrial membrane potential was detected.
Glutamine-supplemented,
> >> > hyperoxia-exposed cells had a  HIGHER  O(2) consumption rate and GSH
> >> > content.
> >>  > Electron and fluorescence microscopy revealed that, in  hyperoxia,
> >> > glutamine
> >> > protected cellular  structures, especially mitochondria, from damage.
> >> > In
> >> >  hyperoxia, activity of the tricarboxylic acid cycle enzyme
> >> >  alpha-ketoglutarate dehydrogenase was partially protected by  its
> > indirect
> >> > substrate, glutamine, indicating a  mechanism of mitochondrial
> > protection.
> >> > THEREFORE:   I take L-Glutamine and DHEA to increase the level of GSH
> >> > in
> >> >  the
> >> > body naturally to further thwart the symptoms and  destruction of
P.D.
> >> > along
> >> > with my other  vitamin/mineral protocol which exclude PD drugs. As a
> > note.
> >>  > I
> >> > never tried the Amantadine. My doctors forced me  early to look
> > elsewhere
> >> > for
> >> > help since they  couldnt due to lack of knowledge or incentive. Not
> >> > sure
> >> >  which but I'm alot healthier for switching to a no drug  protocol.
> >> >
> >> > ----- Original Message -----
> >>  > From: "Ernesto Divo" <[log in to unmask]>
> >> > To:  <[log in to unmask]>
> >> > Sent: Sunday, May 03,  2009 12:24 PM
> >> > Subject: Re: Question re Amantadine  use
> >> >
> >> >
> >> >> Hi John,
> >>  >>
> >> >> I'm 56 and was diagnosed with PD in 2000, I've  been taking Azilect
> >> >> and
> >> >> Requip (Ropinirole) the nausea  form the Requip is unbearable.  I
have
> >> >> introduced  to my regimen for the past 5 months or so, 'MaxGXL', a
> >> >  supplement
> >> >> developed here in the US, by a US scientist  and sold by a US
> >> >> company. It raises thet levels of GSH  in your cells naturally. It
> >> >> took
> >> >> the
> >> >>  GXL about a week to work on my sleeping pattern, I was waking up
2-3
> >> >> times
> >> >> during the night, now I  sleep straight thru the night, and it took
> > about
> >> >>  three weeks to work on my cognitive process but it was so subtle  I
> > barely
> >> >> thought it was the GXL. I wasn't having  problems looking for words
to
> >> > finish
> >> >> a  sentence, my memory is back, I don't lose things around the
house,
> > I
> >> > have
> >> >> more energy and I feel good and my  wife is happier.  It is strange,
> > when
> >> >> I
> >>  >> asked my doctor about it he said Gluta what?  it seems the  medical
> >> > community
> >> >> is keeping the use of  Glutathione (GSH) under wraps, they don't
want
> >> >>  competition...  I order mine from www.maxgxl.com/133282  I  suggest
> >> >> getting
> >> >> as much info as  possible of GSH, I went to www.youtube.com and
> > searched
> >> >  for
> >> >> 'The mother of all antioxidants', there is this  doctor Mark Hyman
who
> >> >> explains in details about GSH;  excellent video.
> >> >>
> >> >> Good luck to  you.
> >> >>
> >> >> Ernesto,
> >> >> Miami,  FL
> >> >>
> >> >> On Sat, May 2, 2009 at 11:46 AM,  john emrys
<[log in to unmask]>
> >> > wrote:
> >>  >>
> >> >> > Hey John
> >> >> >
> >>  >> > I've been on Amantadine since being diagnosed in October  of last
> > year;
> >> >> > dosage has remained constant and  titrated from 100mg to 300mg per
> > day,
> >> > over
> >>  >> > an initial period of 3 weeks.
> >> >>  >
> >> >> > I space the dosing about 5-ish hours apart;  I've found if the
final
> >> >> > dose
> >> >  of
> >> >> > 100mg is taken later than 8PM, I have trouble  sleeping through
the
> >> > night.
> >> >> >
> >>  >> > It does give me an energy boost and some minor relief from
muscle
> >> >> > tightness, but does nothing to improve gait  or reduce tremor.
It's
> > sort
> >> > of
> >> >> >  just a little bit of "gas" for your "engine."
> >> >>  >
> >> >> > On the other hand, I find it causes auditory  hallucinations,
> >> >> > drowsiness,
> >> >> >  occasional vertigo, foggy thought processing and swelling around
> > the
> >> > knees.
> >> >> >
> >> >> > I  find much better results on GSH and mucuna bean, which I
started
> >>  >> > about
> >> > 6
> >> >> > months ago (the  mucuna has been a very recent thing, so it's been
> > too
> >> >  early
> >> >> > to tell – but so far, I'm definitely  impressed). My neuro
> > practically
> >> > lit
> >> >> >  his own hair on fire when I told him, but he couldn't deny  the
> > results
> >> > of
> >> >> > the GSH.
> >>  >> >
> >> >> > The goal is to be able to cut the  amantadine by 35 - 50% within 6
> >> > months.
> >> >>  > My view is the longer I stay away from starting the agonists,
the
> >> > better.
> >> >> >
> >> >> >  Hope that helps.
> >> >> >
> >> >> >
> >>  >> >
> >> >> > Joh
> >> >> >
> >>  >> >
> >> >>
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> >>
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> >
> >
> > **************Remember Mom this Mother's Day! Find a florist near you
now.
> >
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