Hello Brian,

Brian Collins wrote:
>
> On Sun 09 Mar, Joao Paulo Carvalho wrote:
> > Charles Countryman wrote:
> > >es,
> >
> > Against facts there is no arguments...There are old hands in this list
> > that take Sinemet for a long time and found it was the better choice
> > since then as for ex. Brian and others.If I were you I would check with
> > at the least 3 other specialists and then judge.
> >
>
> Hello Joao Paulo, I must have missed your initial email , but I have seen the
> replies. I am, as you indicate, an advocate of early introduction of Sinemet/
> Madopar, with one proviso: that the sinemet is used only to replace the
> missing natural dopamine, and not taken in large doses as I now understand
> some people use it. Using that philosophy (At least in more recent years as
> I learned more about it), I have managed to make effective use of Sinemet
> for 17 years.
<snipped>
> I can see that, by advocating the early introduction of Sinemet, I may have
> appeared to be arguing against the use of agonists, although I am sure that
> I have not specifically  said so. To set the record straight, I consider that
> for the long-term Sinemet user, the introduction of a modest dose of levodopa
> agonist can be beneficial in promoting smoother transitions between on and
> off. Sorry if I have misled anyone.
>

Dear friend, I may assure you that at least in my case you did not
misled about only take levodopa.Neverthless at my present probation with
PD I only take levodopa and 400 u of vitamin E and has worked fine to me
so far.

Best wishes,
   +----| Joao Paulo de Carvalho   |------ +
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   +--------| Salvador-Bahia-Brazil |------+