LISTSERV 16.0 - PARKINSN Archives

Subscriber's Corner

Email Lists

PARKINSN Archives

PARKINSN@LISTSERV.UTORONTO.CA

View:

Message:

[

First

Last

]

By Topic:

[

First

Last

]

By Author:

[

First

Last

]

Font:

Proportional Font

		LISTSERV Archives
		PARKINSN Home
		PARKINSN October 1997, Week 2

Subject:

MEDLINE on the Web - Results

From:

Linda Carlton <[log in to unmask]>

Reply-To:

Parkinson's Information Exchange <[log in to unmask]>

Date:

Thu, 9 Oct 1997 10:23:22 -0400

Content-Type:

text/plain

Parts/Attachments:

text/plain (86 lines)

This is a multi-part message in MIME format.
--------------96A853AFB2529FFF37202DC2
Content-Type: text/plain; charset=us-ascii
Content-Transfer-Encoding: 7bit

http://www.medscape.com/server-java/MedPage?med96-97+309692+(Parkinson+and+HSV)
--------------96A853AFB2529FFF37202DC2
Content-Type: text/html; charset=us-ascii; name="MedPage"
Content-Transfer-Encoding: 7bit
Content-Disposition: inline; filename="MedPage"
Content-Base: "http://www.medscape.com/server-java/Me
        dPage?med96-97+309692+(Parkinson+an
        d+HSV)"

<HTML>
<HEAD>
<TITLE>MEDLINE on the Web - Results</TITLE>
</HEAD>

<BODY bgcolor=ffffff>
<center>
<a href="/cgi-bin/redir.exe?SpaceID=35&AdID=262&URL=http://www.edex.com/med.htm" target="_top"><img src="/Advertising/SchwarzPharma/bl-edex.gif" border=0  alt="Straightforward information for impotence "></a></A><p>

<IMG SRC="http://www.medscape.com/Home/banners.blank.GIF" width=476 height=26 alt="Folio"><p>
<table width=70% border=2>
<tr><td align=center>Search for "(Parkinson and HSV)" in <nobr><a href="/server-java/Keysearch?(Parkinson%20and%20HSV)">Medscape's free Full-Text Articles</a></nobr> or <nobr>the <a href="/server-java/MedBookSearch?(Parkinson%20and%20HSV)">Medscape Bookstore</a></nobr></td></tr>
</table>

</center>



<br><DL>
<!---StartRecord--->
<dt><B>Title</B>
<dd>Development of an HSV-based vector for the treatment of <b><i>Parkinson</i></b>'s disease.</dd>
<dt><B>Author</B>
<dd>Fink DJ; Poliani PL; Oligino T; Krisky DM; Goins WF; Glorioso JC</dd>
<dt><B>Address</B>
<dd>Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pennsylvania 15261, USA.</dd>
<dt><B>Source</B>

<dd>Exp Neurol, 144(1):103-21  1997 Mar
</dd>
<dt><B>Abstract</B>
<dd>The restricted pattern of neurodegeneration seen in <b><i>Parkinson</i></b>'s disease, and the identification of trophic factors that prevent toxin-induced degeneration of dopaminergic neurons, has spurred research into potential gene therapy for this disease. Herpes simplex virus (HSV-1) is a neurotrophic virus which naturally establishes latency in neurons. HSV-based vectors have been demonstrated to transfer and transiently express transgenes in neurons in brain in vivo. Recent experiment have shown that deletion of multiple immediate-early HSV genes reduces the potential cytotoxicity of these vectors, and in addition results in altered patterns of transgene expression that may allow for long-term expression required for human gene therapy applications.</dd>
<dt><B>Language</B>
<dd>Eng</dd>
<dt><B>Unique Identifier</B>
<dd>97271208</dd>
<dt><p>
<hr>
<p>
</dd>
<dt><B>MESH Headings</B>
<dd>Gene Expression; Gene Therapy (*); Genetic Vectors (*); Human; <b><i>Parkinson</i></b> Disease (*TH); Simplexvirus (*GE); Trans-Activation (Genetics)</dd>
<dt><p>
<hr>
<p>
</dd>
<dt><B>Publication Type</B>
<dd>JOURNAL ARTICLE; REVIEW; REVIEW, TUTORIAL</dd>
<dt><B>ISSN</B>
<dd>0014-4886</dd>
<dt><B>Country of Publication</B>
<dd>UNITED STATES</dd>
</dd>
</DL>



</pre>
<p><hr>

<center>http://www.medscape.com<br>

<A HREF="http://www.medscape.com/Home/About.html">Medscape</A> is produced by Medscape, Inc.<br>

All material on this server <A HREF="http://www.medscape.com/Home/Copyright.html">Copyright</A> &copy; 1994, 1995, 1996, 1997 by the publishers involved.<p>

<A HREF="http://www.medscape.com/home/B-Bar.map"><IMG border=0 width=476 height=20 SRC="http://www.medscape.com/Home/B-Bar.GIF" ISMAP alt="Click this icon to load the navigation map (0.9Kb)"></a></center>

</body>
</html>

--------------96A853AFB2529FFF37202DC2--

Top of Message | Previous Page | Permalink

Search Archives

Advanced Options

Options

		Log In
		Get Password

		Search Archives

		Subscribe or Unsubscribe

Archives

ATOM RSS1 RSS2

LISTSERV.UTORONTO.CA