At 04:22 PM 4/18/99 -0700, you wrote:
>Bob....
>
>Your intake of levadopa seems VERY high to me, however as we all
>know what works for one Parkie may not work for another.
>
>Sooooo... if'n whatcha are taking hasn't killed ya (just kidding,
>and heaven forbid!), and ya are feeling pretty decent on that
>dose, then who who are WE to tell ya to take less?
>
>Barb Mallut
>[log in to unmask]
>-----Original Message-----
>From: Bob Bowling <[log in to unmask]>
>To: [log in to unmask] <[log in to unmask]>
>Date: Sunday, April 18, 1999 7:50 AM
>Subject: Re: Sorting out the Agonists
>
>
>>Brian.
>>
>>After perusing some 40-odd responses to the subject survey  I
>note my daily
>>Levodopa intake is roughly twice that of the next highest
>respondent.
>>Accordingly,  I am submitting my responses directly to the List
>(cc to you)
>>in hopes of eliciting responses from other members with high
>Levodopa
>>dosages.  I see a competent Movement Disorder Specialist, self
>medicate with
>>his approval and maintain a fairly normal lifestyle.  I can
>generally avoid
>>other than mild Dyskinesia by reducing a dose by 1/2 tablet of
>25/100
>>Sinemet.
>>
>>1.    Which agonist?  Mirapex
>>
>>2.   When did you begin taking it?  August, 1997
>>
>>3.    When was PD diagnosed?   1989
>>
>>4.     Age when diagnosed?    43
>>
>>5.     When first symptoms noted?    1986
>>
>>6.     Present daily intake of Levodopa?  Approx. 2,000 mg.
>>        (2 X 25/100 q 2 hours plus  50 mg. kickers  as needed--I
>average 1
>>kicker per day.)  The formula                     calculates to
>2400 mg.
>>before kickers but I usually miss two late night doses due to
>sleep.
>>
>>7.    Present agonist intake?  3 X 1.5 mg.=4.5 mg daily
>>
>>8.     Has neuro advised of max safe dose?    Yes, plus it's
>available on
>>any package insert.
>>
>>
>>Bob Bowling
>>Overland Park, KS
>>[log in to unmask]
>>
>Just adding another prescribed dosage FYI, Bob.  My husband, 3 years after
diagnosis,
takes Sinemet CR, 150/600 per day.  Permax is his agonist, 0.45 per day. In
addition,
20mg Prozac per day, in the am, 1 1/2 (2mg tab) Akineton, and 1 5mg tablet
of Altace
per day.

He has always been a sedentary person, and anything but demonstrative, so
family members barely notice that he moves less and with greater effort.
Does a more
physically active person have need for a much larger dose, more often?

MR
>