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> From: Sharon & Jim LeBlanc <[log in to unmask]>
> To: [log in to unmask]
> Subject: Environmental Parkinsons and Twins and Flight Attendant
Parkinsons  Theory
> Date: Thursday, July 15, 1999 10:25 PM
>
> N-Nitrosodimethylamine - Industrial Solvent, Antioxidant, Solvent in
Fiber
> and Plastics Industry; in Lubricants, Condensers to increase dielectric
> constant, Nematocide, Softner for copolymers. Detected in gasoline and
> diesel engine exhaust, emitted from heavy duty diesel engines, wastewater
> effluents, dried sludge, in the air of a number of industries,
> foundry,rubber , chemical,  dye, leather,  fish processing , surfactant
> operations and the ambient air of several large cities. (Spectrum
> Laboratories)
>
> Dimethylamine becomes N-nitrosodimethylamine in air. It is used as an
> accelerator in vulcanizing rubber, tanning, manufacture of soaps,
chemical
> intermediant for dimethylformamide (solvent for acrylic fibers),
> dimethylamine oxide surfactant, dimethylamine salt of dimethylhydrazine
> acid gas absorbent, antioxidants, dyes, flotation agent, gasoline
> stabilizers, pharmaceuticals, electroplating, pesticide propellant,
> attracting boll weevils, missile fuels, rocket propellants, textile
> chemicals, dehairing agent, as a photographic chemical plasticizer, and
as
> an ANTIKNOCK AGENT in Fuels.
> Amines tend to be fat soluble. ADP to ATP happens in brown fat cells with
> the help of nH (Nitrogen) .
> Is disposed of by burning in a safe location or combustible chamber.
> Found in uncultivated soil, in all types of food, coffee, meat packaging,
> plastic building material, INFANT FORMULA.
> INHIBITS TRANSGLUTAMINASE ACTIVITY AND GLUCOSE-STIMULATED INSULIN
RELEASE.
> (Spectrum)
>
> RXR/RXR and RXR/RAR complexes bind to and activate transcription of the
> transglutaminase gene.
> IF TRANSGLUTAMINASE IS INHIBITED, SO IS THE RXR retinoid or
9-cis-retinoic
> acid
> (RXR mutant mice have Parkinsonian Locomotion - Pub Med).
> Two cis-regulatory elements have been identified, a tripartite retinoid
> response element RRE1 and a conserved element HR-1, that cooperate in
> regulating the transcriptional activity of the transglutaminase gene
> promoter.
> TWO CIS ELEMENTS , OR CRE's , retinoids, INHIBIT TRANSGLUTAMINASE.
>
> Clostridium Botulinum makes , N-nitroso-dimethyl-amine and
dimethyl-amine.
> Clostridium also makes N-nitroso -dimethylbutyrate-amine. Butyrate
> increased tumor growth.
> BOTOX is for dystonia in Parkinsons. Negates Acetylcholine. Fully kills
the
> painfully dying nerves.
> Nitrosamines are carcinogenic. N-Nitrosodimethylurea and
> N-nitrosodimethylamine cause skin cancer.
> Jet Fuel also causes Skin Cancer. (NAVY Fuel JP-5)
>
> CREB1 effects both D2 Dopamine Receptors and TCL4 cutaneous cancer.
> Targretin, a retinoid X agonist, booster is for cutaneous cancer and
> diabetes type two.
> CREB2 often binds with C/EBP peroxidase promoter and Parkinsons Disease
is
> a disease of too much lipid peroxidation and not enough of CREB2.
> Targretin effects both cancer and diabetes related to Parkinsons Disease.
> Retinoid X effects both CREB1 and CREB2
>
> IF TRANSGLUTAMINASE IS INHIBITED BY Dimethylamine, AND INHIBITED BY RRE1
> and HR-1, which are both CRE's, I bet one belongs to CREB1 and one
belongs
> to CREB2. And I bet N-nitrosodimethylamine belongs to CREB1 and
> Dimethylamine belongs to CREB2.
>
> So I would gather that the Dimethylamine in the antiknock agent in jet
fuel
> is causing the Parkinsons in airline stewardesses. Aviation gasoline
> contains anti-knock additives (avgas). It is a diesel derivative. Diesel
> and gas fumes, N-Nitrosodimethylamine is condensed, compressed by a
> compressor, exhaust fumes are compressed again in the turbines. The air
is
> hot and has to go through a cooler before it goes into the passenger
cabin.
> Perhaps N-Nitrosodimethylamine is heated, compressed, cooled, into
> Dimethylamine in the process, or somehow fumes from the anti-knock
additive
> are getting into the airplane. Ambient air is full of other airline
diesel
> exhaust and is drawn in from the airport in the first place to use as air
> for inside the airplane and is then condensed and compacted. Whatever
> amount of N-nitrosodimethylamine was in the air would be greater inside
the
> plane. And the passanger cabin is full of flotation devices.
>
> So, depending on the levels of N-nitrosodimethylamine and dimethylamine,
> the twin  effected by n-nitrosodimethylamine would get cancer and the
twin
> effected by dimethylamine would get Parkinsons.  The twin nearest the oil
> furnace would get cancer. The twin not breast fed, but bottle fed, would
> get Parkinsons.
>
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